Glutathione

Glutathione is a tripeptide antioxidant central to cellular protection that people run mainly for skin health, liver support, and detoxification, with liver and antioxidant reports tracking at 100% positive and neurological benefits noted in a smaller cohort. Because community dosing is inconsistent, the only captured clinician guidance suggests 200 mg subcutaneously twice daily on a continuous, non-cycled schedule. The tradeoff is that the off-label evidence base is thinner than the discourse suggests; most exploratory indications rest on trials that have not posted results.

Glutathione

Research Evidence

Evidence shape

Evidence for glutathione is moderate, with the strongest trial reaching Phase 3 and the most data concentrated in Parkinson’s disease, cystic fibrosis, and autism spectrum disorder. Still, only one blinded study has posted results across 13 distinct sponsors, and while 26 indications have been mapped, 23 are thin or exploratory and 21 rest on a single trial. The majority of completed studies have no posted outcomes, leaving the long tail studied but not at scale.

Depthhow much
30 registered trials
14 completed · 1 with posted results · 10 recruiting / active · combined n=60
Breadthhow many areas
26 indications mapped
23 thin / exploratory · 1 animal-only · 21 single-trial long-tail
Qualityhow rigorous
Highest tier: Phase 3
1 blinded with results · 13 distinct sponsors · AE table from NCT03020719 · 6 linked publications on registered trials
Breadth and depth54 rows captured
Human
direct clinical signal
30
Animal
translational support
12
In vitro
mechanistic support
12
HighMediumLow

Anecdotal efficacy

Side effects

Clinical research side effects

Anecdotal side effects

Price

1
US
1500 mg
$35.00
$0.02/mg
2
--
1500 mg
$31.45
$0.02/mg
3
UK
1500 mg
$33.67
$0.027/mg
4
US
1500 mg
$44.99
$0.03/mg
5
US
1200 mg
$39.90
$0.03/mg
6
Fair Oaks, CA, USA
1500 mg
$49.99
$0.03/mg

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Dosing & Protocol

How Glutathione is dosed across research, clinician, and community sources — each evidence tier kept separate so the dose range, frequency, timing, and cycling stay visible without flattening different levels of evidence.

Research trials
Published clinical-trial protocols · n = 14
Typical dose
No quantified dose captured for this tier.
Timing
unspecified
Cycle
unspecified

14 completed trials identified; trial dosing not reliably extracted from registry data.

8 sources
Clinician practice
Doctor & published-protocol guidance · n = 2
Typical dose
200 mg
200 mg
200 mg
Frequency
BID
Timing
unspecified
Route
oral
Cycle
unspecified

Clinician protocols dose 200 mg BID oral (2 sources).

2 sources
Anecdotal
Community-reported real-world use · n = 20
Typical dose
No quantified dose captured for this tier.

No structured protocol details captured for this tier yet.

Community reports indicate Glutathione use across several areas: 4 reports for antioxidant/detox (50% positive), 4 reports for liver support (100% positive), 7 reports for skin health/appearance (85.7% positive), and 5 reports for neurological support (100% positive). Specific dosing details are not consistently available from these anecdotal reports.

Peptide Deep Dive

Peptide Deep Dive is not projected for this peptide yet.

Regulatory safety notes

Warnings and precautions
  • WARNINGS: If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children. In case of overdose, contact a physician or a Poison Control Center right away.
  • Tamper Evident: Sealed for your protection. Do not use if seal is broken or missing.

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